The Physical Effects of Alcohol on Women

                                    The Physical Effects of Alcohol on Women

Women’s bodies react differently to alcohol than men’s bodies and this can be explained by biological differences:

Women have approximately 10% more fatty tissue and less body water than men. This means that women attain a higher blood alcohol concentration (BAC) than men for the same volume of alcohol consumed.

Women have lower levels of alcohol dehydrogenase (ADH), an enzyme involved in the metabolism of alcohol. As a result, women experience the effects of alcohol more quickly, and for longer, than men.  On average, women weigh less than men and, therefore, have less tissue to absorb alcohol.

Women’s hormone levels fluctuate during the menstrual cycle and this

may affect the rate of alcohol metabolism in the body, causing women to

experience higher blood alcohol levels at different points in the cycle.

Although men and women experience many of the same negative physical

effects of excessive alcohol intake, research indicates that, as well as the

harm caused to women and the foetus in pregnancy, women may be more

vulnerable to harm than men, and some risks are specific to women:

Breast cancer

Although many studies have identified alcohol consumption as a risk

factor for breast cancer, the biological mechanisms involved have not been

defined. The international Collaborative Group on Hormonal Factors in

Breast Cancer compared 58,515 women with breast cancer and 95,067

without it. It concluded that up to 4% of breast cancers in the developed

world can be attributed to alcohol and that women drinking six drinks per

day, on average, are 46% more likely to develop breast cancer.

Liver damage

Women develop liver disease at lower drinking levels and after shorter

periods of time, compared to men. They are also more likely to develop

alcoholic hepatitis and to die from cirrhosis of the liver.

Brain damage

Women may be more vulnerable than men to alcohol-induced brain damage.

Views of the brain using magnetic resonance imaging found that a region of

the brain involved in coordinating multiple brain functions was smaller in

alcoholic women than non-alcoholic women and men.

Cognitive impairment

There is some evidence to suggest that women who drink heavily may

be more vulnerable to cognitive impairment than men, and this may have

implications for spatial memory, attention and constructive thinking.

Fertility

Alcohol intake correlates with decreased conception rates. Chronic drinking

can result in inadequate functioning of the ovaries and sometimes cessation

in menstruation. According to a study on the effect of moderate drinking on

fertility, even women with a weekly alcohol intake of five or fewer drinks

experienced reduced fertility. Couples trying to conceive may consider not

drinking alcohol as it may affect the quality of the egg and sperm prior to

conception.

Oral contraception

Contraceptives delay the absorption of alcohol into the bloodstream;

therefore, women taking oral contraceptives may not become intoxicated as

quickly as they would normally.

Osteoporosis

Osteoporosis is a debilitating bone thinning disorder where bones become

fragile and more susceptible to fracture, affecting more women than men.

Studies have indicated that heavy drinking, particularly in adolescence or

young adult years, can dramatically compromise bone quality and may

increase osteoporosis risk in later life. Further evidence suggests that bones

do not overcome the damaging effects when alcohol use is discontinued.

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